BDBM50536216 CHEMBL4580425

SMILES CCc1cc(O)c(F)cc1-c1cc(NS(=O)(=O)CC2CCC2)c2cn[nH]c2c1

InChI Key InChIKey=VQNDDNOJLMXOHA-UHFFFAOYSA-N

Data  5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536216   

TargetNon-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK1/Tyrosine-protein kinase JAK2/Tyrosine-protein kinase JAK3(Homo sapiens (Human))
Leo Pharma

Curated by ChEMBL

LigandBDBM50536216(CHEMBL4580425)Copy SMILESCopy InChI

Affinity DataIC50:  398nMAssay Description:Inhibition of JAK in human B lymphocyte cells assessed as suppression of IL4-induced STAT6 phosphorylation preincubated for 1 hr followed by IL4 addi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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